Preheat Air Fryer Set to 400°F (200°C) for 3 minutes.
Season the Fish: Pat tilapia dry. Lightly brush or spray both sides with oil. In a small bowl, combine paprika, garlic powder, onion powder, and black pepper. Sprinkle evenly over both sides of the fish.
Air Fry: Place fillets in a single layer in the basket. Cook 8–10 minutes, flipping halfway, until the fish is opaque and flakes easily (internal temp 145°F / 63°C).
Serve: Squeeze fresh lemon juice over fillets. Garnish with parsley or cilantro.
Pair with steamed vegetables, quinoa, or a leafy green salad for a balanced, heart-healthy meal.